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Promethazine Promethazine is a phenothiazine spinoff, which differs structurally within the antipsychotic phenothiazines because of the existence of the branched side chain and no ring substitution.
are pregnant. Utilization of Promethazine Hydrochloride and Codeine Phosphate Oral Solution throughout pregnancy can cause withdrawal signs and symptoms in your newborn child that can be lifestyle-threatening Otherwise identified and taken care of. Tell your Health care service provider instantly Should you be pregnant or Imagine you may well be pregnant. •
Selling or giving away Promethazine Hydrochloride and Codeine Phosphate Oral Solution might hurt Many others, which is from the law. Tell your healthcare provider In case you have ever abused or been depending on Liquor, prescription medicines or Avenue medication.
Existence-threatening respiratory troubles (respiratory despair). Promethazine Hydrochloride and Codeine Phosphate Oral Resolution might cause breathing complications (respiratory melancholy) that can happen Anytime in the course of procedure and can lead to Loss of life. Your danger of respiratory troubles is greatest when you 1st get started getting Promethazine Hydrochloride and Codeine Phosphate Oral Remedy, are getting other medicines that can result in breathing troubles, have certain lung issues, are aged or have sure other health problems.
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Endocrine/Metabolic: Scenarios of serotonin syndrome, a likely existence-threatening issue, happen to be documented for the duration of concomitant use of opioids with serotonergic medicine.
In certain Women of all ages, this transpires in a short time. Codeine and morphine pass into your breast milk. A great deal of morphine could cause your infant to die.
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Drug interactions, including an elevated incidence of extrapyramidal consequences, are actually reported when some MAOI and phenothiazines are utilized concomitantly.
Monitor clients using a historical past of seizure Issues for worsened seizure Handle throughout promethazine HCl and codeine phosphate oral Remedy therapy.
Stay away from the use of promethazine HCl and codeine phosphate oral solution in patients who're taking CYP3A4 inducers. If concomitant utilization of a CYP3A4 inducer is critical, follow the affected individual for lessened efficacy.
Will not acquire any benzodiazepines or medicines that can result in drowsiness or sleepiness all through therapy with Promethazine Hydrochloride and Codeine Phosphate Oral Remedy. Question your healthcare service provider for an index of these medicines if You aren't positive.